Source and Transmission of Vibiro cholera causing Cholera in Nepal
Cholera, an acute diarrheal disease caused by toxigenic strains of Vibrio cholerae, remains major killer disease world-wide. Though being absolutely preventive and curable disease, significant number of people dies annualy of cholera in Nepal especially during epidemics due to poor sanitation and lack of education and health facilities. Because Vibrio cholera has been proved to be an autochthonous organism of natural water bodies, study on its source and transmission becomes crucial especially indeveloping countries like Nepal with poor sanitary condition. CMDN/INPL, in collaboration with International Center for Medical Science (KCMS), has been carrying out a molecular metagenomics (environmental genomics) based study in outbreak areas like Doti, Bajhang and Kathmandu of Nepal.